136 projects
Status
Organization Type
COVID-19 and air quality - effects and interactions
Against the background of the global COVID-19 outbreak and the increasing number of confirmed infections Europe, a shutdown of all non-essential businesses took place. Besides lower emissions from industries the amount of traffic declined significantly, especially in regions with a high commuter amounts. Traffic is an important source of fine particles, and due to their size and chemical composition they pose a high risk to human health. On a global scale PM has led to >3.3 million premature deaths and has been associated with diseases like acute lower respiratory illness or COPD. Furtherm...
COVID-19 and the Jurisprudence of Hypotheticals
During the last century, the human race faced several epidemics. Some of them had relatively limited impact on economic, political and social consequences like Ebola, and SARS. Other types of epidemics had major impact on economic, political and social formulation, like 1918 Flu. A question about the impact of COVID-19 is whether will it have limited or major impact on the near future. In December 2019, the COVID-19 starts to spread in the City of Wuhan, China. Scientists were split between two major groups. First, many scientists failed to expect to the widespread of the epidemic beyo...
COVID-19 related economic implications in Luxembourg: services industry robustness and commercial...
The proposed project seeks to understand crucial short- and medium-term economic impacts on and strategies of Luxembourg's commercial real estate industry (offices, hotels, large retail) as a proxy for its services industries' crisis resilience. Luxembourg is a small but open economy. The finance and advanced business services (FABS) are strategic industries and main contributors to Luxembourg's GDP. Close links between FABS firms (business ties, finance relationships) can amplify shocks in Luxembourg's economy. The likely damage done to the finance sector depends also on how flexible real...
COVID-19, MEntal HEalth, REsilience and self-REgulation (COME-HERE)
Humans are a social species, and their health, life and genetic legacy are threatened by social isolation. Like other animals, humans fare poorly when isolated. The preventive measures to contain the current COVID-19 outbreak limit all forms of physical social contacts to a minimum, more and earlier in some countries than in others. Differences exist also within the same country due to household composition and dwelling location. Social isolation is associated with ill health. In this project we will investigate which factors predict levels of psychological distress and well-being associate...
COVID19 Literature Bio-Curation, Text-mining and Semantic Web Technologies
The world wide scientific response to COVID-19 pandemic is reflected in the ever-growing scientific literature. Enriching our current knowledge base (https://biokb.lcsb.uni.lu) with these publications requires joint efforts at each stage of the chain of process involved in the text-mining pipeline. This pipeline comprises several challenging tasks such as part-of-speech tagging, entity recognition and normalisation, or event extraction, which are essential to discover relevant knowledge in the form of entities, relations and events. Such knowledge is then made available to the public via se...
COVID19-induced changes to the plasma proteome
Studies focussing on human coronavirus found so far seven different viruses including SARS, MERS and COVID19. SARS, MERS and COVID19 present with various flu-like symptoms up to respiratory distress. Secondary symptoms include kidney problems, cardiovascular problems and neurological signs, like headache and nausea. In the case of the SARS infection, it has been shown that the virus can invade the central nervous system in patients and laboratory animals. The infection of epithelial cells by a coronavirus will lead to a change of the cellular protein composition in response to the virus' ...
CRISIS - Correlates of Resilience In the context of Social Isolation in Seniors
In the current COVID-19 crisis, older adults are at particular risk for severe health outcomes and increased mortality. Whereas it is of prime importance to raise public awareness regarding the special risk of older people, and reduced in-person contact is essential to protect vulnerable groups, we have to take into account what effects these measures have on subjective well-being, mental health and further development of older persons. The present research project will tackle the question of how current measures and their communication to the public are experienced by the target group (60...
Cell-cell interaction model of COVID19 for potential interventions
The emergence of COVID-19 pandemic implies new challenges for the Health Systems worldwide. The great majority of COVID-19 infections are mild and self-limiting in nature. Nevertheless, a small percentage of the patients require hospitalisation and specialised attention in Intensive Care Units (ICUs). The role of host immune responses in clearance of COVID-19 or the role, if any, of host immune responses in contributing to severe respiratory pathogenesis of COVID-19 infections is not known at this time. There are previously identified specific host immune response chemokine and cytokine sig...