11 projects
Status
Organization Type
A dynamic model of the COVID-19 tuned for different countries: a systems-biological tool for the ...
A dynamic model of COVID-19 epidemics recently developed (video: https://youtu.be/lbsqJ1_WvmE, model: https://jjj.bio.vu.nl/models/westerhoff1/simulate/, ref: https://medrxiv.org/cgi/content/short/2020.03.29.20045039v1) will be tuned for different countries to analyze the effect of different measures in the anticipation of next epidemics. Models will be available for online simulations at JWS Online (https://jjj.bio.vu.nl/models/westerhoff1/simulate/), and used for the development of computer tutorials for systems biological studies.
A unified web-based platform for viral phylogeny, proteomics and genomics research in real-time
We propose the development of an integrated web-based data exploration tool for genomics, proteomics, phylogeny, evolutionary and geographical data on SARS-CoV-2 samples from Luxembourg supporting researchers and physicians to gauge the potential impact of viral evolution on virulence and transmission dynamics but also the efficacy of molecular detection methods. Integrating different data sources and visualisation modes through a graphical web-interface will offer a unique perspective on the pathogen and serve as tools to assess potential imminent risks.
Controling the symptoms
Since the information about the COVID-19 pandemic isn't that much available. The easiest and fastest way to mitigate the virus is by controlling the symptoms.
DICO-Lux: DIgital Covid-19 Observatory In LUXembourg: An Open Tool For SARS-COV-2 Crisis Manageme...
Monitoring online activities for public health purposes has been investigated since the first days of the digital epidemiology field early 2010s, with the objective of capturing health-related trends and model disease outbreaks. Most famous examples of internet surveillance were developed for the flu, influenza AH1N1, the Zika virus or Ebola. We now have the opportunity to leverage both the digital data available online and the appropriate Natural Language Processing (NLP) and Text Mining methods to fight the Covid-19 pandemic. The main objective of the DICO-LUX project is to rapidly d...
Innovative end-to-end solution for respiratory diseases detection and genotyping
Our innovative end-to-end solution for respiratory diseases detection and genotyping is composed of 3 main compoenets as follows: First, we want, through a multiplex qPCR assay, to target and differentiate in priority COVID-19, SARS, H5N1, H1N1 (devastating diseases) from seasonal flu (under control). Second, we propose to develop an NGS and SANGER assay for the following Intended uses: Respiratory diseases Genotyping, Screening, Monitoring, Quasispecies identification, Epidemiological studies. Third, we target to establish a large COVID-19 and SARS worldwide database , compare patient ...
Investigating the role of COmpanion and LIVEstock animals in the Epidemiology of SARS-CoV-2 in Lu...
Almost all Coronaviruses (CoVs) affecting human, including human CoV-NL63, -229E, -OC43, SARS-CoV and MERS-CoV, have a zoonotic origin. Similarly, phylogenetic and recombination analyses strongly suggested a zoonotic origin for SARS-CoV-2. After adaptation to human, some zoonotic viruses retain the capacity of infecting animals, as regularly shown for influenza A virus. There is a raising concern that SARS-CoV-2 virus may have a host switching potential as well. Anecdotic cases already suggest that Canidae and Felidae are susceptible to SARS-CoV-2 infection. Experimental intranasal infectio...
Low-cost breath sensors for SARS-CoV-2 for home usage
Based on our research on liquid crystal droplets and shells demonstrating their responsiveness to specific substances in their surrounding, e.g. lipids, I would like to explore the possibility of making low-cost tests for SARS-CoV-2 that people can use in their home. We also make polymer fibers in our labs, and by using the right polymer, we can make a filter that a persons breathers through (mounted in, e.g., a face mask), and then the filter is dissolved in water, which is the natural surrounding for our liquid crystal droplets and spheres. If viruses have been caught in the filter, they ...
Luxembourg Weizmann Initiative
Contribution to data collection effort to inform the decision making process on the pandemic exit scenario based on the Weizmann initiative adapted to Luxembourg