2 projects

Multi-omics evaluation of microbial co-infection as marker of COVID-19 severity -(CO-INFECTOMICS)

The main goal of this project is to understand if SARS-CoV2 co-infections are a predictive marker of disease severity in the Luxembourgish population. To achieve this, the study will compare the respiratory and stool samples of mild and severe SARS-CoV2 positive patients. Using metagenomics and metatranscriptomics, microbial profiles of the respiratory and intestinal tracts will be investigated, with a specific attention for co-infections. Moreover, individual microbial profiles will be correlated to the health parameters and immune response. We hope that the CO-INFECTOMICS project will ena...

Innovative end-to-end solution for respiratory diseases detection and genotyping

Our innovative end-to-end solution for respiratory diseases detection and genotyping is composed of 3 main compoenets as follows: First, we want, through a multiplex qPCR assay, to target and differentiate in priority COVID-19, SARS, H5N1, H1N1 (devastating diseases) from seasonal flu (under control). Second, we propose to develop an NGS and SANGER assay for the following Intended uses: Respiratory diseases Genotyping, Screening, Monitoring, Quasispecies identification, Epidemiological studies. Third, we target to establish a large COVID-19 and SARS worldwide database , compare patient ...

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