114 projects

Comparative antiviral efficacy of different autophagy inhibitors against COVID-19 infection

As of April 28, 2020, worldwide, over 3 million people have been diagnosed and over 211,000 deaths with ongoing deadly coronavirus disease-19 (COVID-19) also known as SARS coronavirus 2 (SARS-CoV-2/2019-nCoV). Currently, there is no approved treatment against COVID-19. Vaccines are under development, but they will take at least one year before reaching to the population. A fast track approach would be to reuse already approved drugs that have been broadly tested through multiple clinical trials. Virophagy is a catabolic autophagic pathway used by mammalian cells to destroy viruses. Viruses ...

Covid-19, Politics and Religion

The proposed interdisciplinary research will elaborate on the impact of COVID-19 on the social operation of religion at a Luxembourgish and European level. The research is divided in a theoretical and an empirical part. The theoretical part aims at identifying the place of religion as an element within the dominant discourse on COVID-19.The empirical approach will explore the potential changes in religiosity after COVID-19, as well as their possible reflection in party politics. In particular, it will explore the following research themes: a) The possible effect of COVID-19 on public opi...

COVoiceID - Identification of COVID-19 from Voice

COVoiceID project proposes a machine learning based system that will use patient's voice and cough to detect repeating patterns, with the aim to discriminate between voices of healthy individuals and COVID-19 patients. COVID-19 is a respiratory condition, affecting breathing and voice, and causing, among other symptoms, dry cough, sore throat, excessively breathy voice and typical breathing patterns. These are all conditions that can make patients' voice distinctive, creating recognizable voice signatures. The ability to successfully identify COVID-19 patients from their voice will heavily...

COVID-19 time-space analysis on Twitter

Coronavirus outbreak perception in the population of the greater region on Twitter: spatio-temporal distribution and salient subtopics.

ReDesign Europe - Post-Pandemic Paradigm Change in EU Law

This project aims to respond to the vacuum of sound legal rules and principles into which decision-makers risk to sink while developing constructive trajectories for the post-pandemic crisis legislation. Such vacuum places significant risks to the legal frameworks that have governed our societies in the context of European integration, under the changes prompted by reactions to the crisis

Leveraging Systems Biology to Target Hyperinflammation in COVID-19

The emergence of COVID-19 pandemic implies new challenges for the Health Systems worldwide. A small percentage of the patients require hospitalisation and specialised attention in Intensive Care Units (ICUs). Furthermore, accumulating evidence suggests that a subgroup of patients with severe COVID-19 might have a cytokine storm syndrome. Therefore, the main goal of the proposal is to elucidate the potential role of cytokine storm in COVID-19 disease severity, and to propose novel strategies for counteracting this hyperinflammatory response. In this context, we propose to develop a single...

Protection against Infection through regulatory law - ProLaw

The pandemic spread of the SARS-Cov-2 virus hit the states of liberal democracies unprepared. Medicine lacks both drugs and clinically tested vaccines, and the health system as such quickly proved to be structurally overburdened. Above all, the democratic constitutional states of the West were not legally prepared for the pandemic. In Luxembourg, the measures to contain the virus were initially based on a law dating from 1885, before the regulation of 18 March 2020 was introduced as a legal basis with reference to the establishment of the 'Etat de Crise' in accordance with Art. 32.4 of the ...

Compulsory health training for future pandemics

One of the key challenges that many countries, particularly Luxembourg, is facing during the pandemic is the shortage of health practitioners. Without a doubt being trained in health practice has lots of restrictions, rules, and regulations as it is concerned with lives of human beings. Nevertheless, what I'm suggesting here needs lots of refinement and consultations with health experts/professionals to draw out a final applicable solution. The basic idea is that since this pandemic, as many politicians have put it out, is a war against humanity, I'm suggesting that we prepare our citizens ...

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