114 projects

COVI-NUTRI-METABOLOMICS

Background: A poor nutrient status due to sub-optimal dietary habits increases risk of viral infections. In particular, individuals with low vitamin D, A and E, as well as zinc plasma levels are less likely to develop immune-responses against influenza vaccines. Vitamin C supplementation improves conditions in individuals with acute respiratory infections in some studies. Dietary fiber is inversely correlated with mortality from respiratory/infectious disease. These nutrients are paramount for optimal immune-response, are implicated in oxidative stress, inflammatory processes, and viral rep...

DEEPHOUSE - Deep Mining with the Covid-19 Data Warehouse

The Johns Hopkins University Center for Systems Science and Engineering (JSU-CCSE) has compiled a number of various data sources including data from the World Health Organization, the European Centre for Disease Prevention and Control, and many others. JSU-CCSE maintains and regularly updates the data so that one can assume a trusted data quality. The published data itself is largely time-series data and covers worldwide mortality rates, infected and recovered cases of the Covid-19 disease for more than 200 countries. JSU-CCSE has recorded the data itself in various Excel files; this enable...

Modeling the macroeconomic and distributional effects of Covid-19 and restarting scenarios (MODVid)

MODVid is a set of four complementary and interdependent work packages involving 6 PI's and about 20 partners from Unilu, STATEC, LISER and international institutions. Two WP's aim to inform public decisions during the crisis. They provide estimates of the macroeconomic, distributional, and epidemiological effects of the crisis and of restarting scenarios in Luxembourg. These outputs will be delivered within one to two months. Other WP's aim to inform public decisions in the aftermath of the crisis. They address medium-term effects on the industry and occupational structure of the labor for...

Emerging spatial interactions in cities, towns and rural landscapes at a time of crises

This project will explore emerging spatial interactions in our towns, cities and rural areas during social distancing measures. New knowledge outlining the evolving uses of public spaces and infrastructures is essential to support our understanding of the unintended consequences of epidemic control decisions. As well as providing a discourse for public dialogue. We will gather an evidence base to inform public policy on the consequences of new spatial interactions and their consequences for urban and rural environments. Our findings will answer questions and predict the impact of behavioura...

Mobidemia (Modelling and Monitoring Human Mobility Patterns Affecting the Spread and Control of I...

The Covid19 pandemic has highlighted the critical role of restricting activities and movement to limit the spread of infectious diseases: transmission occurs at activity locations (workplaces, groceries, parks). Each region has its own mix of travel behaviours, activity locations, transport infrastructure and unique space-time patterns of human contacts. Epidemiological models don't capture this heterogeneity and are not city/region specific. However, it's difficult to determine which businesses and activities should stop and for how long, and which transport services are needed. This st...

Using historical knowledge graphs to materialize and visualize Corona viruses knowledge evolution...

Knowledge Graphs (KG) or, more generally speaking, Knowledge bases implemented using Semantic Web technologies provide the basics to represent domain knowledge in a machine interpretable manner. This allows computers to consume this knowledge for various purposes (e.g. information retrieval, knowledge discovery, decision support...). Because of their properties, KG are currently used to formalize knowledge about Covid 19 to provide a deep understanding of the state of knowledge about the disease at a given moment in time (e.g. CORD 19, Lens Covid 19 datasets, John Hopkins university dataset...

Impact of hypoxia on COVID-19 infection in lung epithelial cells

The international spread of coronavirus disease 2019 (COVID-19) has recently caused over 120.000 deaths in Europe and 200.000 worldwide. The clinical picture goes from the absence of symptoms to critical conditions requiring admission to resuscitation units. The molecular pathways involved in COVID-19 infection and pathogenesis are still being explored. 'Silent hypoxia' is considered by some physicians as an early indicator of COVID-19 viral infection in patients. A key step in COVID-19 infection is the viral entry into pulmonary alveoli epithelial cells, leading to the disruption of surf...

Covid-19 related LOckdown: Shift in Exposures to neighbourhood environments and changes in Physic...

A lockdown state implies radical changes in our lifestyle, especially physical activity (PA), while PA plays a central role in maintaining an adequate health status, counteracting the negative consequences of numerous diseases. We aim to investigate the impact of lockdown (and quarantine) on PA patterns based on retrospective data. We will analyse the intra-individual changes in PA patterns of participants stratified in two specific subgroups of interest, namely positive cases and their household members as a result of the lockdown/quarantine measures in place, with respect to the partici...

export results as excel

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