2 projects
Status
Domain
Organization Type
Cytokines as biomarkers and therapeutic targets in COVID-19 infection
Cytokines play an important role in the pathogenesis of COVID-19 infection. A subgroup of patients develops a cytokine storm syndrome, correlating with a bad clinical outcome. For example, the concentration of the inflammatory cytokine Interleukin-6 (IL-6) has been recognized as a risk factor for mortality and for respiratory failure in Chinese and German patient cohorts, respectively. Tocilizumab, an antibody directed against the IL-6 receptor alpha chain, is used in clinical trials as well as an FDA-approved inhibitor of Jaks, tyrosine kinases which mediate the signal transduction of mult...
Communication4Care
In a nutshell: Communication4Care (Com4Care) is a cloud-based communication platform to facilitate GDPR conform interoperability and link of relevant (sensor) data with structured patient-related information. No data files need to be exchanged and the platform provides a secure data storage and (real time or asynchronous) communication channel. Thus, improved standardized data acquisition, process monitoring, and data interpretation are possible. The patient can collect and report individual findings and outcomes (PROMs) and 'distribution of information' or sending of data files (electronic...