158 projects
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Cell-cell interaction model of COVID19 for potential interventions
The emergence of COVID-19 pandemic implies new challenges for the Health Systems worldwide. The great majority of COVID-19 infections are mild and self-limiting in nature. Nevertheless, a small percentage of the patients require hospitalisation and specialised attention in Intensive Care Units (ICUs). The role of host immune responses in clearance of COVID-19 or the role, if any, of host immune responses in contributing to severe respiratory pathogenesis of COVID-19 infections is not known at this time. There are previously identified specific host immune response chemokine and cytokine sig...
Privacy Preserving Covid-19 Data Analytics Platform
The COVID-19 pandemic comes with an urgent need of exchanging confidential patient information among local and regional health organizations. Sharing knowledge is crucial for disease surveillance, protecting public health, fighting misinformation and managing the virus outbreak. Medical service providers are required to disclose facts about admissions, transfers and discharges to various entities like the patient's primary care practitioner and post-acute-care services providers. The dissemination of patients' medical records is subject to malicious activities. Most of the current sol...
The cultural determinants of the Covid-19 diffusion
The aim of our research proposal is to undertake an empirical approach that will allow us to understand the cultural determinants of COVID-19 spread in all European countries, USA, China and Canada. The project will identify and quantify the impact of a number of cultural determinants on the virus diffusion such as interpersonal trust, trust in government, political parties and institutions, gender roles in society given that men and women have different degrees of risk aversion, compliance to rules, the degree of socialization and of integration of old people in societies. In view of the d...
Relation of severity of COVID-19 infection to nutrient status, oxidative stress, inflammation & v...
Background: Severity of COVID-19 infection is related to host-factors including the immune and respiratory system, gut health, and pre-existing cardio-metabolic diseases. Enhanced inflammation and oxidative stress may worsen the prognosis of COVID-19 subjects. An imbalanced diet poor in essential micronutrients, dietary fiber and phytochemicals and containing insufficient proteins and antioxidant properties can aggravate these aspects, worsening the immune system and infection risk, especially in conjunction with enhanced visceral adiposity exacerbating chronic inflammation. Individuals wit...
Socio-economic impacts of COVID-19: collecting the data
The aim of this project is to investigate the socio-economic impact of COVID-19, including employment, activity and travel patterns, health behaviours and health. The COVID-19 pandemic is still ongoing in Luxembourg and neighbouring countries. It is currently hoped that due to confinement measures the number of infected persons and deaths will decline in the near future. Public authorities in Luxembourg are considering to relieve the confinement measures to 'unlock' parts of economic and social life in the country as soon as the pandemic is becoming less severe and more 'manageable'. As Lu...
Middle generation and middle class before the post-covid19 recession, Income, wealth and health i...
Young-mid-aged adults (YMAA) - typically in the first decades of their entry in the labour market - make strategic choices in a context of uncertainty, such as home ownership, debt and saving balance, and wealth strategies, which have strong impacts in the long run. Before covid19, apart from the 2008 financial crisis, relative stability, easier access to credit, and the rapid growth of the housing index (with different magnitudes across countries) favored home ownership; early investment (through debt) favored capital gains. The later the decision to buy, the smaller the surface a househol...
Logistic support for mass testing and exit strategy in the COVID-19 crisis using drones
In the current COVID-19 crisis, logistic support for mass testing as well as for any exit strategy is of utmost importance. Therefore, we propose the application of drones with autonomous in- and outdoor navigation capability as a very helpful support measure. Herein, the focus is on two scenarios: (I) the automatic rapid aerial transport of tests between test centers or hospitals and the laboratories to support the mass testing and (II) the automatic aerial disinfection of larger in- and outdoor spaces as a part of the exit strategy. In both scenarios, application of drones to automate the...
DICO-Lux: DIgital Covid-19 Observatory In LUXembourg: An Open Tool For SARS-COV-2 Crisis Manageme...
Monitoring online activities for public health purposes has been investigated since the first days of the digital epidemiology field early 2010s, with the objective of capturing health-related trends and model disease outbreaks. Most famous examples of internet surveillance were developed for the flu, influenza AH1N1, the Zika virus or Ebola. We now have the opportunity to leverage both the digital data available online and the appropriate Natural Language Processing (NLP) and Text Mining methods to fight the Covid-19 pandemic. The main objective of the DICO-LUX project is to rapidly d...
