3 projects
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Tracking SARS-CoV-2 with Open Banking API
According to the health authorities , due to the highly contagious potential of the SARS-CoV-2 (COVID-19 desease), the formal preventive quarantine has been replaced by an isolation strategy early March. However, such strategy cannot last for an undetermined period of time, since there is no concrete date for releasing a vaccine or discovering an effective medicine. The return of people to normal activities will probably happen gradually, but still it will create a new potential peak of cases if not made carefully. Thus, a post-isolation strategy needs to be well planned as the next phase....
Functional characterization of COVID-19 patient gut microbiome
While COVID-19 is mainly considered an airway and lung disease, up to 79% of patients present with gastrointestinal symptoms and recent studies report on the presence of SARS-CoV-2 viral RNA and particles in stools of infected patients, suggesting that the gastrointestinal (GI) tract may have a more important role in disease pathology or transmission than previously thought. The GI tract is also the site of the dense and diverse microbiome, which has the ability to regulate intestinal and systemic immunity through the conversion of dietary nutrients into bioactive metabolites. Consequently,...
COVID-19 and Neurturin
SARS-Cov-2 is a coronavirus is at the origin of the current COVID-19 pandemic, which poses a global and significant threat to public health worldwide. Although several treatment modalities have been evaluated, none has allowed a therapeutic breakthrough until now. New treatment modalities are therefore urgently needed. We have previously described that neurturin, a member of the glial cell line-derived neurotrophic factor family, expressed not only as a growth factor in the nervous system but also the immune system, displays clear anti-inflammatory properties in mouse asthma models. Indeed,...
