21 projects

COVID-19 DIAGNOSTIC PROGRAM POWERED BY AI

The aim of the project is to create a prototype of an integrated tele-medical system supporting comprehensive clinical decisions in the field of novel COVID-19. The project scope also includes significant research activities focused on utilising a variety of available multidisciplinary clinical and imaging data to enable the proposed system to go beyond supporting detection and diagnosis that is already possible by the existing methods. The problem undertaken in the project is the limitations related to the early diagnosis of the COVID-19, collection of epidemiological and statistical data ...

TraAct-DD - Track and Act with Data Donation #getout #stayout

Luxembourg is entering a gradual deconfinement phase. For this to be successful, it is critical that the country protect vulnerable people and build the trust of the population in going back to work, to school safely. It is also vital to identify asymptomatic COVID-positive patients and to wisely direct the (scarce) tests. If Luxembourg can manage this, epidemiological models indicate that a gradual release of the population may stem the pandemic and enable return to normal (#getout, #stayout). The ongoing debate at the government level indicates hesitation between blue-tooth tracing, ma...

CardioCube: COVID AI-driven conversational agent

CardioCube COVID enables virtual care for patients with coronavirus and quarantined individuals using AI-driven conversational agents deployed on smartphones and smart speakers. Automatic forward triage system allows to multiply healthcare provider's workforce increasing patients and providers safety thorough physical distancing. CardioCube COVID will include following modules: 1. Clinical Follow-Up - periodically, using mobile or voice interface, user answers a set of clinical questions to evaluate the health status at home. CardioCube red-flags patients/quarantined individuals at-r...

Pocket Rehab - mHealth-based Rehabilitation Program for patients with cardiovascular disease as p...

Cardiovascular diseases remain the major cause of mortality with an estimated prevalence of 422.7 million cases worldwide at high cost for the public health. Recently, the pathophysiological mechanism of the coronavirus uses the angiotensin-converting enzyme 2 (ACE2) as a functional receptor, increasing the risk of contamination and the mortality rate in this population, aggravating this scenario. According to the epidemiological bulletin of COE-COVID19 of the Ministry of Health of Brazil, among the 1124 deaths recorded until 11 April 2020, in those under the age of 60, 82.5% had illness a...

Digital Health Passport

With the lockdown exit, all public places must allow the safe reception of a large part of the population. To do this, it will be essential to detect symptomatic individuals, while respecting their rights and dignity, in order to protect them, but also protect others. We propose a Digital Health Passport (DHP), a mobile application, which is part of this process. The citizen will therefore have at hand a sesame which will allow him to integrate the public places of his choice. This DHP will contain information about his state of health, only that related to the Covid 19, namely the results ...

Covid-19 related LOckdown: Shift in Exposures to neighbourhood environments and changes in Physic...

A lockdown state implies radical changes in our lifestyle, especially physical activity (PA), while PA plays a central role in maintaining an adequate health status, counteracting the negative consequences of numerous diseases. We aim to investigate the impact of lockdown (and quarantine) on PA patterns based on retrospective data. We will analyse the intra-individual changes in PA patterns of participants stratified in two specific subgroups of interest, namely positive cases and their household members as a result of the lockdown/quarantine measures in place, with respect to the partici...

Easy ambulatory diagnostic profilometry for Covid19 symptoms tracking: computed in Luxembourg

This project contributes to the following work packages: WP01: Infection prevalence, WP02: Predictive markers for covid-19 severity, WP05:real-time epidemiological data on COVID-19 positive or suspected cases treated in the ambulatory setting, WP07 : map and analyse COVID-19 incidence in Luxembourg, WP05 : exit strategy and 'controlled return to normalisation'. In order to easily track symptoms and severity of Covid19 diagnosed or suspected subjects, we propose a simple ambulatory diagnostic system for creating a functional capacity profilometry of an individual with modular approaches i...

An integrative network-based drug repurposing approach for COVID-19

We aim at analyzing the publicly available transcriptomics data generated by exposing human lung epithelial cells to SARS-CoV particles and measuring the differences in the gene expression. We will use a molecular network analysis approach to identify a set of key genes, that represent key regulators in the SARS-CoV gene expression signature. This signature will be filtered to distinguish pathological from protective responses and used to identify drugs that could potentially reverse pathological features of the disease phenotype based on the anti-correlation of known drug-response gene exp...

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